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Infection incidence, timing, and predictors in newly diagnosed multiple myeloma: a real-world retrospective cohort study

Abstract: Infections are a leading cause of morbidity and mortality in multiple myeloma (MM), particularly during the induction phase. Identifying real-world infection patterns…

Date: 2026-05-14

HOPX is required for the generation of umbilical cord blood-derived memory-like NK cells induced by three cytokines

Abstract: Natural killer (NK) cells represent a highly promising form of cancer immunotherapy. Recent studies have utilized umbilical cord blood (UCB) as a source of NK cells and…

Date: 2026-05-14

Relationship between hemoglobin levels and diabetic retinopathy in Chinese type 2 diabetes mellitus populations: a cross-sectional study

Abstract: Diabetic retinopathy (DR) remains one of the leading causes of visual impairment worldwide. Recent studies have suggested that hemoglobin (Hb) levels may be associated…

Date: 2026-05-14

A serum exosomal four-miRNA signature for the diagnosis of central precocious puberty: a discovery and validation study

Abstract: The current diagnosis of central precocious puberty (CPP) relies on the invasive and time-consuming GnRH stimulation test. There is an urgent need for convenient,…

Date: 2026-05-14

Associations of systemic immune-inflammation index and aggregate index of systemic inflammation with acute gouty arthritis in men: a cross-sectional study

Abstract: This study aims to evaluate the associations of complete blood cell count-derived inflammatory markers—including monocyte-to-lymphocyte ratio (MLR),…

Date: 2026-05-14

Minimally invasive 1 mm skin biopsies capture site-specific transcriptomic heterogeneity in vitiligo

Abstract: Vitiligo is a chronic inflammatory skin disease characterized by clinical and molecular heterogeneity across lesional, perilesional and non-lesional skin within the same…

Date: 2026-05-14

Italian regional variation in amenable mortality 2015/2019: impact of outsourcing, expenditures and socio-economic variables

Abstract: This study addresses the need to monitor regional performance in decentralized health systems and determine the main variables associated with regional variability.…

Date: 2026-05-14

Randomized clinical trials and informed consent in pediatric oncology: a Nordic comparative study of parents’ experiences

Abstract: In pediatric oncology, randomized clinical trials are an integral part of standard treatment. Because enrollment typically must occur before therapy begins, families…

Date: 2026-05-14

Higher plasma omega-6 fatty acids are associated with lower dementia risk: evidence from NMR metabolomics and Alzheimer's disease polygenic risk in the UK Biobank

Abstract: Circulating polyunsaturated fatty acids (PUFAs) have been implicated in neurodegenerative processes, yet epidemiological evidence remains inconsistent. Genetic…

Date: 2026-05-14

Functional data analysis of FSH and inhibin B levels in four ovulatory cycles shows a changing oscillatory interaction during the follicular phase

Abstract: The pituitary hormone FSH (follicle-stimulating hormone) and the follicular granulosa cell hormone inhibin B are important in follicle development ending in ovulation.…

Date: 2026-05-14