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Enhanced independent discriminative performance of elevated lipoprotein(a) for cardiovascular outcomes in patients with diabetes: a comparative analysis of optimal cutoff values

Abstract: This study aimed to evaluate the independent discriminative performance of elevated Lipoprotein(a) [Lp(a)] in identifying prevalent cardiovascular disease (CVD),…

Date: 2026-04-21

Effect of a nursing-based information–motivation–behavioral model on older patients with type 2 diabetes mellitus

Abstract: Older patients with type 2 diabetes mellitus (T2DM) frequently encounter challenges, including a diminished capacity for self-management, a high prevalence of negative…

Date: 2026-04-21

Development and validation of a diagnostic nomogram for Wagner grade?2 diabetic foot ulcers in hospitalized patients with type 2 diabetes

Abstract: Diabetic foot ulcers (DFUs) represent a severe and prevalent complication of diabetes, contributing to substantial disability and elevated mortality. This study aimed to…

Date: 2026-04-21

Identification and validation of a nomogram for psoriasis diagnosis: a novel biomarker combination with stable high expression in the early stage

Abstract: Psoriasis is a complex chronic inflammatory skin disease. While typical cases are often diagnosed based on clinical features, achieving objective assessment of disease…

Date: 2026-04-21

Interpretable two-stage deep learning for pediatric obstructive sleep apnea diagnosis using lateral cephalograms

Abstract: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a prevalent sleep-breathing disorder in pediatrics, yet early and accurate detection remains challenging due to the…

Date: 2026-04-21

Prognostic factors for cardiovascular-related mortality in pediatric hypertrophic cardiomyopathy: a retrospective cohort study with survival analysis and X-tile stratification

Abstract: To identify prognostic factors associated with cardiovascular-related mortality in children with hypertrophic cardiomyopathy (HCM) and to explore outcome-oriented risk…

Date: 2026-04-21

Development and internal validation of a multivariable risk stratification model for preoperative anxiety in surgical patients: a retrospective observational study

Abstract: Preoperative anxiety is common among surgical patients and is associated with adverse perioperative outcomes. Early identification of patients at elevated risk of…

Date: 2026-04-21

Pre-diagnostic vitamin D deficiency and subsequent thyroid cancer risk: a propensity-matched cohort study

Abstract: Vitamin D deficiency (VDD) has been implicated as a potential risk factor for thyroid cancer; however, existing evidence is derived primarily from case-control or…

Date: 2026-04-21

The differential role of anesthetic technique by etiology of postpartum hemorrhage: a dual-cohort analysis of emergency cesarean delivery and placenta accreta spectrum

Abstract: Based on the hypothesis that the effect of general anesthesia (GA) vs. neuraxial anesthesia (NA) on postpartum hemorrhage (PPH) varies according to its underlying…

Date: 2026-04-21

Prevalence and associated factors of oral frailty in elderly patients undergoing elective surgery: a secondary analysis of a cross-sectional study

Abstract: Oral health has become a critical area of public health concern. Oral frailty refers to a significant decline in oral function and health, often manifested as impaired…

Date: 2026-04-21